PRMT5 FUNCTION AND TARGETING IN CANCER

PRMT5 function and targeting in cancer

Protein methyl transferases play critical roles in numerous regulatory pathways that underlie willy wonka book week costume cancer development, progression and therapy-response.Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as extrinsic microenvir

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Determination of Reasonable Bottom-Hole Pressure in Unconventional Tight Oil Reservoirs: A Field Case Investigation

AbstractThe bottom-hole flow pressure is an important factor affecting the production of the unconventional tight oil well.The reasonable bottom-hole flow pressure has a positive effect on enhancing the production capacity of oilfields and improving the production efficiency of oilfield enterprises.Therefore, a robust method is proposed to determin

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PENGARUH PLASTICIZER PADA KARAKTERISTIK EDIBLE FILM DARI PEKTIN

EFFECT OF PLASTICIzER ON THE PECTINIC EDIBLE FILM CHARACTERISTICS.The peel of Balinese Citrus contains high concentration of pectin which can be further processed to be edible films.The edible films can be utilized as a food coating which protects the food from any external mass transports such as humid, oxygen, and soluble material and can be serv

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Informing Marine Protected Area Designation and Management for Nesting Olive Ridley Sea Turtles Using Satellite Tracking

Understanding the horizontal and vertical habitat of olive ridley sea turtles (Lepidochelys olivacea), a threatened species, is critical for determining regions for protection and relevant gear modifications that may effectively reduce bycatch, the largest threat to this species.Satellite transmitters were used to determine the movement and dive be

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Visualizing Vpr-induced G2 arrest and apoptosis.

Vpr is an accessory protein of human immunodeficiency virus type 1 (HIV-1) with multiple functions.The induction of G2 arrest by Vpr plays a particularly important role in efficient viral replication because the transcriptional activity of the HIV-1 long terminal repeat is most active in G2 phase.The regulation of apoptosis by Vpr is also important

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